Gastrosplenic fistula due to splenic lymphoma: two case reports and review of the literature

Autor: Feryel Letaief Ksontini, Yosra Zaimi, Isaad Nefzi, Salim Khrouf, Myriam Ayari, Sonia Sghaier, Asma Zidi, Houcine Magherbi, Mouna Ayadi
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Journal of Medical Case Reports, Vol 18, Iss 1, Pp 1-4 (2024)
Druh dokumentu: article
ISSN: 1752-1947
DOI: 10.1186/s13256-024-04441-2
Popis: Abstract Background Gastrosplenic fistula is a rare and potentially fatal complication of various conditions. Lymphoma is the most common cause. It can occur spontaneously or after chemotherapy. Gastrosplenic fistula diagnosis can be confused with a splenic abscess because of the presence of air into the mass. The computed tomography identification of the fistulous tract is the key to a right diagnosis. Treatment modalities include surgical resection, chemotherapy, or a combination of both. Case presentation Here we report two patients with gastrosplenic fistula due to diffuse large B cell lymphoma. The first patient was a 54-year-old Caucasian woman with an enormous primary splenic diffuse large B cell lymphoma leading to the development of a spontaneous fistula in the stomach. The second patient was a 48-year-old Caucasian male patient with an enormous splenic diffuse large B cell lymphoma complicated by fistula after chemotherapy. Both patients died of septic shock several days after surgery. Conclusion Gastrosplenic fistula is a rare complication with a poor-prognosis, for which surgery is currently the preferred treatment.
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