Mild COVID-19 has no detrimental effect on semen quality

Autor: Philippos Edimiris, Cornelius Doehmen, Lisa Müller, Marcel Andrée, Dunja Maria Baston-Buest, Sebastian Buest, Ortwin Adams, Jan-Steffen Krüssel, Alexandra Petra Bielfeld
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Basic and Clinical Andrology, Vol 33, Iss 1, Pp 1-8 (2023)
Druh dokumentu: article
ISSN: 2051-4190
DOI: 10.1186/s12610-023-00190-2
Popis: Abstract Background As of today, the effect of coronavirus disease 2019 (COVID-19) on male fertility remains unclear. Studies published so far have partly contradictory results, likely due to very small sample sizes and heterogeneous populations. To gain a deeper understanding of the impact of COVID-19 on male fertility, we performed a prospective case–control study, in which we examined the ejaculate of 37 subjects, including 25 subjects in the acute phase of mild COVID-19 and 12 subjects who did not suffer from COVID-19. Determination of semen parameters, severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) qPCR, and infectivity analysis were performed in the acute phase of the disease and in series. Results Semen parameter values did not differ significantly between subjects with mild COVID-19 and the control group. The serial examination of semen parameters revealed no significant changes between 4, 18, and 82 days after the onset of symptoms. SARS-CoV-2 RNA or infectious particles could not be detected in any ejaculate. Conclusion Mild COVID-19 seems to have no detrimental effect on semen parameter values.
Databáze: Directory of Open Access Journals