| Autor: |
Leonardo A. Calderon, Rodrigo G. Stábeli, Juliana P. Zuliani, Andreimar M. Soares, Anderson M. Kayano, Rodrigo S. Silva, Kayena D. Zaqueo, Gustavo H. M. F. Souza, Cleópatra A. S. Caldeira, Antonio Coutinho-Neto |
| Jazyk: |
angličtina |
| Rok vydání: |
2013 |
| Předmět: |
|
| Zdroj: |
Toxins, Vol 5, Iss 2, Pp 327-335 (2013) |
| Druh dokumentu: |
article |
| ISSN: |
2072-6651 |
| DOI: |
10.3390/toxins5020327 |
| Popis: |
A bradykinin-potentiating peptide (BPP) from Amazon Bothrops atrox venom with m/z 1384.7386 was identified and characterized by collision induced dissociation (CID) using an ESI-MS/MS spectra obtained in positive ion mode on a hybrid Qq-oaTOF mass spectrometer, Xevo G2 QTof MS (Waters, Manchester, UK). De novo peptide sequence analysis of the CID fragmentation spectra showed the amino acid sequence ZKWPRPGPEIPP, with a pyroglutamic acid and theoretical monoisotopic m/z 1384.7378, which is similar to experimental data, showing a mass accuracy of 0.6 ppm. The peptide is homologous to other BPP from Bothrops moojeni and was named as BPP-BAX12. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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