Age and gender as determinants of the bone quality of the greater tuberosity: A HR-pQCT cadaver study

Autor: Kirchhoff Chlodwig, Braunstein Volker, Milz Stefan, Sprecher Christoph M, Kirchhoff Sonja, Graw Mathias, Imhoff Andreas B, Hinterwimmer Stefan
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: BMC Musculoskeletal Disorders, Vol 13, Iss 1, p 221 (2012)
Druh dokumentu: article
ISSN: 1471-2474
DOI: 10.1186/1471-2474-13-221
Popis: Abstract Background Age-dependent trabecular changes of the humeral head might weaken the fixation of suture anchors used for rotator cuff (RC) repair. This might lead to suture anchor loosening and thus compromise the integrity of the repair. The aim of this study was to analyze whether the trabecular microstructure within the RC footprint is influenced by age, gender or handedness. Methods Axial HR-pQCT scans (Scanco Medical) of 64 freshly frozen cadaveric human humeral head specimens (age 72.3 ± 17.4 years) were analyzed to determine the bone volume-to-total volume ratio (BV/TV), trabecular thickness (Trab Th), trabecular number (Trab N) and connectivity density (Conn Dens). Within the RC footprint, 2 volumes of interest (VOI), posteromedial (PM) and anterolateral (AL) and one control VOI in the subarticular bone (SC) were set. Results The highest BV/TV was found in SC: 0.22 ± 0.06% vs. PM: 0.04 ± 0.05% vs. AL: 0.02 ± 0.04%; p Conclusions The presented microarchitectural data allow for future subtle biomechanical testing comprising knowledge on age- and sex-related changes of the tuberosities of the humeral head. Furthermore, the insights on the trabecular structure of the humeral head of the elderly may lead to the development of new fixation materials in bone with inferior bone quality.
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