Autor: |
Maria L. Cristina, Cristiano Alicino, Marina Sartini, Valeria Faccio, Anna M. Spagnolo, Valerio D. Bono, Giovanni Cassola, Anna M. De Mite, Maria P. Crisalli, Gianluca Ottria, Elisa Schinca, Giuliano L. Pinto, Luigi C. Bottaro, Claudio Viscoli, Andrea Orsi, Daniele R. Giacobbe, Giancarlo Icardi |
Jazyk: |
angličtina |
Rok vydání: |
2018 |
Předmět: |
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Zdroj: |
Journal of Infection and Public Health, Vol 11, Iss 2, Pp 171-177 (2018) |
Druh dokumentu: |
article |
ISSN: |
1876-0341 |
DOI: |
10.1016/j.jiph.2017.06.003 |
Popis: |
In the last decade, carbapenem-resistant Klebsiella pneumoniae (CR-Kp) has become endemic in several countries, including Italy. In the present study, we assessed the differences in epidemiology, management, and mortality of CR-Kp bloodstream infection (BSI) in the three main adult acute-care hospitals of the metropolitan area of Genoa, Italy.From January 2013 to December 2014, all patients with CR-Kp BSI were identified through the computerized microbiology laboratory databases of the three hospitals. The primary endpoints of the study were incidence and characteristics of CR-Kp BSI in hospitals within the same endemic metropolitan area. Secondary endpoints were characteristics of CR-Kp BSI in hospitals with and without internal infectious diseases consultants (IDCs) and 15-day mortality.During the study period, the incidence of healthcare-associated CR-Kp BSI in the entire study population was 1.35 episodes per 10,000 patient-days, with substantial differences between the three hospitals. Patients admitted to the two hospital with internal IDCs were more likely to receive post-susceptibility test combined therapy including carbapenems (77% vs. 26%, p |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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