Efficacy of a standardized herbal formulation from Glycyrrhiza glabra L. as an adjuvant treatment in hospitalized patients with COVID-19: A Randomized Controlled trial

Autor: Saeed Soleiman-Meigooni, Nafiseh Hoseini Yekta, Hamid Reza Sheikhan, Mohammad Aminianfar, Ramin Hamidi-Farahani, Mousa Ahmadi, Ali Asgari, Mohammad Hasan Kazemi-Galougahi, Roja Rahimi
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Journal of Ayurveda and Integrative Medicine, Vol 13, Iss 4, Pp 100670- (2022)
Druh dokumentu: article
ISSN: 0975-9476
DOI: 10.1016/j.jaim.2022.100670
Popis: Introduction: As no specific pharmacological intervention has been known for COVID-19, medicinal plants may be a suitable candidate for management of this disease. The aim of this study was to investigate the efficacy of a herbal syrup from licorice as an adjuvant treatment in hospitalized patients with COVID-19. Materials and methods: 213 hospitalized patients diagnosed with COVID-19 were assigned to receive either standardized licorice syrup as an adjuvant treatment plus standard care [Syrup Group (SYRUP), N = 91], or standard care alone [Standard Group (STANDARD), N = 104], for 7 days. The primary endpoint was duration of hospitalization in survivors. The secondary endpoints included 25% increase in oxygen saturation, C-reactive protein (CRP) difference and lymphocyte difference from baseline, number of death and number of patients transferred to ICU. Results: Mean duration of admission was 5.24 days in SYRUP and 7.14 days in STANDARD (p
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