Risk factors of esophagojejunal anastomotic leakage after total gastrectomy for gastric and Siewert type II/III esophagogastric cancer: a retrospective analysis from a tertiary hospital

Autor: Junjie Liu, Jinzhi Hu, Jiaming Fang, Yingliang Chen, Yonghe Chen, Jiasheng He, Zijian Deng, Junsheng Peng, Lei Lian, Shi Chen
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Frontiers in Oncology, Vol 14 (2024)
Druh dokumentu: article
ISSN: 2234-943X
DOI: 10.3389/fonc.2024.1481278
Popis: Background and objectivesTo detect the risk factors associated with esophagojejunal anastomotic leakage (EJAL) after total gastrectomy for gastric and Siewert type II/III esophagogastric cancer.MethodsThe data for 609 patients underwent Roux-en-Y esophagojejunostomy after total gastrectomy between March 2015 and March 2021 were reviewed. Univariate and multivariate analyses were performed to evaluate the risk factors.ResultsEJAL was observed in 48 (7.9%) of 609 patients. Univariate analysis revealed that gender, the number of comorbidities (hypertension, diabetes mellitus, coronary heart disease and chronic obstructive pulmonary disease), postoperative serum albumin, tumor location, duration of operation were risk factors associated with EJAL. Patients who had the following factors including male, the number of comorbidities ≥2, postoperative serum albumin
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