Predictive modeling of in vivo response to gemcitabine in pancreatic cancer.
| Autor: | James J Lee, Justin Huang, Christopher G England, Lacey R McNally, Hermann B Frieboes |
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| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: | |
| Zdroj: | PLoS Computational Biology, Vol 9, Iss 9, p e1003231 (2013) |
| Druh dokumentu: | article |
| ISSN: | 1553-734X 1553-7358 |
| DOI: | 10.1371/journal.pcbi.1003231 |
| Popis: | A clear contradiction exists between cytotoxic in-vitro studies demonstrating effectiveness of Gemcitabine to curtail pancreatic cancer and in-vivo studies failing to show Gemcitabine as an effective treatment. The outcome of chemotherapy in metastatic stages, where surgery is no longer viable, shows a 5-year survival |
| Databáze: | Directory of Open Access Journals |
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