New Conjugated Benzothiazole-N-oxides: Synthesis and Biological Activity

Autor:	Pavlína Foltínová, Peter Magdolen, Pavol Zahradník, Peter Gajdoš
Jazyk:	angličtina
Rok vydání:	2009
Předmět:	benzothiazole N-oxides push-pull systems antibacterial Euglena gracilis Organic chemistry QD241-441
Zdroj:	Molecules, Vol 14, Iss 12, Pp 5382-5388 (2009)
Druh dokumentu:	article
ISSN:	14125382 1420-3049
DOI:	10.3390/molecules14125382
Popis:	Eleven new 2-styrylbenzothiazole-N-oxides have been prepared by aldol – type condensation reactions between 2-methylbenzothiazole–N-oxide and para-substituted benzaldehydes. Compounds with cyclic amino substituents showed typical push-pull molecule properties. Four compounds were tested against various bacterial strains as well as the protozoan Euglena gracilis as model microorganisms. Unlike previously prepared analogous benzothiazolium salts, only weak activity was recorded.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/f7c5849805a34ccaa08ac1b2bef62008 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF