Increase in the frequency of lower extremity venous reflux in male patients with hypertension receiving combination of an angiotensin-converting enzyme inhibitor and a calcium channel blocker

Autor: S. V. Letyagina, V. M. Baev, T. Yu. Agafonova
Jazyk: ruština
Rok vydání: 2021
Předmět:
Zdroj: Кардиоваскулярная терапия и профилактика, Vol 20, Iss 1 (2021)
Druh dokumentu: article
ISSN: 1728-8800
2619-0125
DOI: 10.15829/1728-8800-2021-2578
Popis: Aim. To study the effect of combined antihypertensive therapy (AHT) with an angiotensin-converting enzyme (ACE) inhibitor and a calcium channel blocker on the parameters of lower extremity venous reflux in males with hypertension (HTN).Material and methods. The study involved 46 men 30-50 years old with uncontrolled HTN, among whom 23 patients with chronic venous disease (CVD) were identified. The dynamics of the rate, temporal and velocity parameters of lower extremity venous reflux was analyzed for a 14-15-day period using combined AHT (lisinopril, 10 mg/day; amlodipine, 5 mg/day). Reflux was assessed at rest by ultrasound of symmetric superficial, deep and perforator veins.Results. As a result of treatment, 40 patients achieved the first target office systolic blood pressure (BP) level (
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