Antithrombotic management of patients with acute coronary syndrome and atrial fibrillation undergoing coronary stenting: a prospective, observational, nationwide study

Autor: Leonardo Bolognese, Pasquale Caldarola, Andrea Rubboli, Leonardo De Luca, Lucio Gonzini, Stefano Urbinati, Adriano Murrone, Fortunato Scotto di Uccio, Fabio Ferrari, Fabiana Lucà, Donata Lucci, Domenico Gabrielli, Andrea Di Lenarda, Michele Massimo Gulizia
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: BMJ Open, Vol 10, Iss 12 (2020)
Druh dokumentu: article
ISSN: 2044-6055
DOI: 10.1136/bmjopen-2020-041044
Popis: Objective The aim of the study was to assess current management of patients with atrial fibrillation (AF) and acute coronary syndrome (ACS) undergoing coronary stenting.Design Non-interventional, prospective, nationwide study.Setting 76 private or public cardiology centres in Italy.Participants Patients with ACS with concomitant AF undergoing percutaneous coronary intervention (PCI).Primary and secondary outcome measures To obtain accurate and up-to-date information on pharmacological management of patients with AF admitted for an ACS and undergoing PCI with stent implantation.Results Over a 12-month period, 598 consecutive patients were enrolled: 48.8% with AF at hospital admission and 51.2% developing AF during hospitalisation. At discharge, a triple antithrombotic therapy (TAT) was prescribed in 64.8%, dual antiplatelet therapy (DAPT) in 25.7% and dual antithrombotic therapy (DAT) in 8.8% of patients. Among patients with AF at admission, TAT and DAT were more frequently prescribed compared with patients with new-onset AF (76.3% vs 53.8% and 12.5% vs 5.3%, respectively; both p
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