Anaplastic lymphoma kinase positive variant of anaplastic large cell lymphoma: A rare entity

Autor: Venkata Satya Ramesh Thummala, Sreenidhi Banda, Vinay Kumar Reddy Kundoor, Kotya Naik Maloth
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: Journal of Indian Academy of Oral Medicine and Radiology, Vol 26, Iss 4, Pp 432-435 (2014)
Druh dokumentu: article
ISSN: 0972-1363
0975-1572
DOI: 10.4103/0972-1363.155640
Popis: Anaplastic large cell lymphoma (ALCL) is a distinct clinicopathological entity of non-Hodgkin′s lymphoma, which has been included as a T-cell neoplasm in the World Health Organization classification, with peculiar features such as painless lymphadenopathy, swelling of extranodal and endoreticular organs, intraoral swellings, and characteristic hallmark cells (eccentric, kidney-shaped, or horseshoe-shaped nuclei) and cluster of differentiation 30 (CD30) positivity. Thorough clinical, biochemical, immunohistochemical, histopathological, and radiological evaluation aids in accurate diagnosis and management of the disease. Here, we report a case of anaplastic lymphoma kinase positive variant of ALCL in a 13-year-old boy.
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