The neonatal microbiome in utero and beyond: perinatal influences and long-term impacts

Autor: Hill Lee, Sharma Ruchika, Hart Lara, Popov Jelena, Moshkovich Michal, Pai Nikhil
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Journal of Laboratory Medicine, Vol 45, Iss 6, Pp 275-291 (2021)
Druh dokumentu: article
ISSN: 2567-9430
2567-9449
DOI: 10.1515/labmed-2021-0131
Popis: The neonatal microbiome offers a valuable model for studying the origins of human health and disease. As the field of metagenomics expands, we also increase our understanding of early life influences on its development. In this review we will describe common techniques used to define and measure the microbiome. We will review in utero influences, normal perinatal development, and known risk factors for abnormal neonatal microbiome development. Finally, we will summarize current evidence that links early life microbial impacts on the development of chronic inflammatory diseases, obesity, and atopy.
Databáze: Directory of Open Access Journals