| Autor: |
Chandra Shekhar, Rajesh Nasam, Siva Ramakrishna Paipuri, Prakash Kumar, Kiranmai Nayani, Srihari Pabbaraja, Prathama S. Mainkar, Srivari Chandrasekhar |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Tetrahedron Chem, Vol 4, Iss , Pp 100033- (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2666-951X |
| DOI: |
10.1016/j.tchem.2022.100033 |
| Popis: |
The emergence and rapid spread of coronavirus disease 2019 (COVID-19), a potentially fatal disease, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has swiftly led to public health crisis worldwide. Hence vaccines and antiviral therapeutics are an important part of the healthcare response to combat the ongoing threat by COVID-19. Here, we report an efficient synthesis of nirmatrelvir (PF-07321332), an orally active SARS-CoV-2 main protease inhibitor. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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