Localization of TSH-secreting pituitary adenoma using 11C-methionine image subtraction

Autor:	Daniel Gillett, Russell Senanayake, James MacFarlane, Merel van der Meulen, Olympia Koulouri, Andrew S. Powlson, Rosy Crawford, Bethany Gillett, Nick Bird, Sarah Heard, Angelos Kolias, Richard Mannion, Luigi Aloj, Iosif A. Mendichovszky, Heok Cheow, Waiel A. Bashari, Mark Gurnell
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	11C-methionine PET Human pituitary tumors Normalization Subtraction imaging Medical physics. Medical radiology. Nuclear medicine R895-920
Zdroj:	EJNMMI Research, Vol 12, Iss 1, Pp 1-10 (2022)
Druh dokumentu:	article
ISSN:	2191-219X
DOI:	10.1186/s13550-022-00899-7
Popis:	Abstract Background Pituitary adenomas (PA) affect ~ 1:1200 of the population and can cause a wide range of symptoms due to hormone over-secretion, loss of normal pituitary gland function and/or compression of visual pathways, resulting in significantly impaired quality of life. Surgery is potentially curative if the location of the adenoma can be determined. However, standard structural (anatomical) imaging, in the form of MRI, is unable to locate all tumors, especially microadenomas (
Databáze:	Directory of Open Access Journals
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