The Value of Sentinel Lymph Node Biopsy in Oral Cavity Cancers

Autor: İsa Kaya, Sercan Göde, Kerem Öztürk, Göksel Turhal, Araz Aliyev, Serdar Akyıldız, Ülkem Yararbaş Duygun, Ümit Uluöz, Atilla Yavuzer
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Turkish Archives of Otorhinolaryngology, Vol 53, Iss 2, Pp 62-66 (2015)
Druh dokumentu: article
ISSN: 2667-7474
DOI: 10.5152/tao.2015.1178
Popis: Objective:The aim of this study was to establish the effectiveness of sentinel lymph node biopsy in the detection of metastasis in N0 necks of T1-T2 early-stage oral cavity cancers.Materials and Methods:Twenty neck dissections were performed in 18 patients diagnosed with T1 and T2 oral cavity cancer, with an indication for elective neck dissection between November 2007 and January 2011. The male to female ratio was 12:8, with a mean age of 54.5 years (range 28-76). Eight of the dissections were performed for lower lip cancer, 7 for tongue cancer, and 5 for floor of the mouth cancer. Sentinel lymph node biopsy was used to detect metastatic lymph nodes. Tc99m radionuclide injection was administered to the periphery of the tumor 24 h before the operation, and a lymphoscintigraphy image was obtained 30 min after the injection. Sentinel lymph nodes were localized and excised on the day of surgery using static lymphoscintigraphy images and a gamma probe. Sentinel lymph nodes were sent for a frozen section examination, and either a selective or a comprehensive neck dissection was performed for each neck according to the results.Results:After the final histopathological examination of the specimens, the negative predictive value, the positive predictive value, the accuracy of the sentinel lymph node biopsy, and frozen section accuracy were found to be 100%.Conclusion:Sentinel lymph node biopsy was found to be an efficient method in the pathological staging and management of the N0 neck in early T-stage oral cavity cancers.
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