Antimicrobial Prescription Pattern in Ho Teaching Hospital, Ghana: Seasonal Determination Using a Point Prevalence Survey

Autor: Cornelius C. Dodoo, Emmanuel Orman, Thelma Alalbila, Adelaide Mensah, Jonathan Jato, Kwadwo A. Mfoafo, Isaac Folitse, Araba Hutton-Nyameaye, Inemesit Okon Ben, Paapa Mensah-Kane, Emmanuel Sarkodie, Eneyi Kpokiri, Misha Ladva, Benedict Awadzi, Yogini Jani
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Antibiotics, Vol 10, Iss 2, p 199 (2021)
Druh dokumentu: article
ISSN: 2079-6382
DOI: 10.3390/antibiotics10020199
Popis: A standardised Global Point Prevalence Survey (PPS) tool was used to determine the antimicrobial prescription pattern in the Ho Teaching Hospital on two separate occasions in a total of 14 wards in the hospital, including dedicated wards for paediatrics and neonates. Manually collected and anonymised data were entered, validated, analysed and reported using a web-based global PPS application. With 147 and 153 patients considered in the July 2019 and January 2020 surveys, respectively, 98 patients (66.7%) and 84 patients (54.9%) had received one or more antimicrobials. The prevalence of antimicrobial use in the adult wards was 64.3% (72/112) and 53.4% (63/118) in the first and second surveys, respectively. The prevalence in the paediatric wards was 60.0% (12/20) and 62.5% (10/16), respectively, in the two surveys, while that in the neonatal wards was 93.3% (14/15) and 57.9% (11/19), respectively. β-lactams were the most used antibiotics in both periods. Malaria was the most common diagnosis requiring the use of antimicrobials in July 2019, accounting for 19.4% of the diagnoses, whereas in January 2020, it was skin and soft-tissue conditions (28.1%). This reflects a seasonal association between malaria and rainfall patterns. Out of the antimicrobials prescribed during each of the survey periods, 95% were used for empirical treatment, and this could be attributed to a number of reasons, including logistical challenges, among others, that require further exploration in the context of local, national and international policy recommendations.
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