| Autor: |
Xing-Guang Zhang, Yan-Qi Zhang, Qian-Peng Cheng, Yi Cao, Jian-Min Sun, Xiao-Feng Lv |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Předmět: |
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| Zdroj: |
European Journal of Medical Research, Vol 23, Iss 1, Pp 1-11 (2018) |
| Druh dokumentu: |
article |
| ISSN: |
2047-783X |
| DOI: |
10.1186/s40001-018-0304-2 |
| Popis: |
Abstract Background The oxidative stress resulting from increased production of ROS plays a crucial role in the development of diabetic complications. We aim to explore the relationships between oxidative stress, diabetic nephropathy (DN) and short-term insulin pump intensive therapy (insulin therapy). Methods Levels of 8-hydroxy-deoxyguanosine (8-OHdG), 3-nitrotyrosine (3-NT), glutathione (GSH), superoxide dismutase (SOD) and Interleukin-6 (IL-6) were estimated before and after 2 weeks of insulin therapy in normal group (NC) and type 2 diabetic (DM) with normal albuminuria (NA), microalbuminuria (MA) and clinical albuminuria (CA). Results In DM group, levels of 8-OHdG and 3-NT were higher than those in NC group (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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