| Autor: |
A. Messaoud, R. Mensi, A. Mrad, A. Mhalla, I. Azizi, B. Amemou, I. Trabelsi, M. H. Grissa, N. Haj Salem, A. Chadly, W. Douki, M. F. Najjar, L. Gaha |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
|
| Zdroj: |
Annals of General Psychiatry, Vol 16, Iss 1, Pp 1-8 (2017) |
| Druh dokumentu: |
article |
| ISSN: |
1744-859X |
| DOI: |
10.1186/s12991-017-0144-4 |
| Popis: |
Abstract Background Patients with major depressive disorder (MDD) have a high risk of suicide. Many pathophysiological factors involved in MDD and suicide such us a low cholesterol levels have been associated with MDD and increased vulnerability to suicide. In this study, we investigate the relation between lipid parameters and suicide risk in patients with MDD. Methods Plasma levels of total cholesterol, triglycerides, and high-density lipoprotein cholesterol (HDL-c) and low-density lipoprotein cholesterol (LDL-c) were determined in 160 patients meeting the DSM-IV-TR criteria for MDD (110 patients without suicidal behavior and 52 suicidal attempters) and 151 healthy controls. Results A significant decrease in plasma cholesterol levels was observed in the group of suicidal depressive patients compared to those without suicidal behavior (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
