Hemorrhagic manifestations of cerebral amyloid angiopathy: from pathogenesis to clinical significance
Autor: | A. A. Kulesh, V. E. Drobakha, V. V. Shestakov |
---|---|
Jazyk: | ruština |
Rok vydání: | 2018 |
Předmět: | |
Zdroj: | Неврология, нейропсихиатрия, психосоматика, Vol 10, Iss 3, Pp 4-11 (2018) |
Druh dokumentu: | article |
ISSN: | 2074-2711 2310-1342 45689245 |
DOI: | 10.14412/2074-2711-2018-3-4-11 |
Popis: | The paper characterizes the neuropathological aspects of cerebral amyloid angiopathy (CAA) and its pathogenesis. It presents in detail the current neuroimaging markers of CAA and their neuropathological correlates. The phenotypic heterogeneity of the disease and its main clinical manifestations are considered; the updated Boston diagnostic criteria are formulated. The issues of intracerebral hemorrhages, cerebral microbleeding, and cortical superficial siderosis, which are associated with CAA, are elucidated in detail. CAA is noted to be of clinical significance for the determination of therapeutic policy in hemorrhagic stroke, systemic thrombolytic therapy, and cognitive impairment. |
Databáze: | Directory of Open Access Journals |
Externí odkaz: |