Review of Literature on Akkermansia muciniphila and its Possible Role in the Etiopathogenesis and Therapy of Type 2 Diabetes Mellitus

Autor:	Made Indira Dianti Sanjiwani, I Putu Hendri Aryadi, I Made Siswadi Semadi
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	Akkermansia muciniphila ER stress gut microbiota insulin resistance probiotic type 2 diabetes mellitus Diseases of the endocrine glands. Clinical endocrinology RC648-665
Zdroj:	Journal of the ASEAN Federation of Endocrine Societies, Vol 37, Iss 1 (2022)
Druh dokumentu:	article
ISSN:	0857-1074 2308-118X
DOI:	10.15605/jafes.037.01.13
Popis:	Akkermansia muciniphila is a promising gut microbiota for the treatment of type 2 diabetes mellitus (T2DM). A. muciniphila stimulates intestinal wall integrity, is an anti-inflammatory agent, and reduces endoplasmic reticulum stress, lipogenesis and gluconeogenesis. These properties make A. muciniphila a potential treatment option for T2DM by reducing insulin resistance and increasing insulin sensitivity and glucose tolerance in different tissues. This article explores the possible role of A. muciniphila in T2DM management, along with the various methods known to modulate A. muciniphila.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/f75e334cff8a4a3d91a6f18c649e4488 Zobrazit plný text záznamu View record in DOAJ