Sleep state misperception: is there a CNS structural source?

Autor: Giselle de Martin Truzzi, Igor de Lima Teixeira, Lucila Bizari Fernandes do Prado, Gilmar Fernandes do Prado, Sergio Tufik, Fernando Morgadinho Coelho
Jazyk: angličtina
Předmět:
Zdroj: Sleep Science, Vol 14, Iss Special 1, Pp 94-96
Druh dokumentu: article
ISSN: 1984-0659
1984-0063
DOI: 10.5935/1984-0063.20200039
Popis: Introduction: We describe a case of sleep state misperception in a patient with a neurotoxoplasmosis lesion in the left nucleocapsular region. Case report: A 40-year-old female patient presented relating sleeplessness over the past 2 years, concurrent with progressive headaches, dizziness and motor and sensory deficits in the right upper and lower limbs. She had a history of AIDS, on irregular antiretroviral therapy and neurotoxoplasmosis. A polysomnography confirmed the hypothesis of sleep state misperception, and magnetic resonance imaging revealed a residual lesion in the left nucleocapsular region.Conclusion: Different models consider that the sleep state misperception could be correlated to structural abnormalities of the central nervous system. A recent study showed that the medial prefrontal cortex had a lower activation in patients with unrefreshing sleep due to chronic fatigue syndrome. This case report highlights the possibility of sleep state misperception having - at least partially - an anatomical substrate in the left nucleocapsular region.
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