Methods for SARS-CoV-2 hospital disinfection, in vitro observations
| Autor: | Dora E. Corzo-Leon, Hadeel Mohammed Abbood, Rosa A. Colamarino, Markus F.C. Steiner, Carol Munro, Ian M. Gould, Karolin Hijazi |
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| Jazyk: | angličtina |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | Infection Prevention in Practice, Vol 6, Iss 1, Pp 100339- (2024) |
| Druh dokumentu: | article |
| ISSN: | 2590-0889 44159145 |
| DOI: | 10.1016/j.infpip.2024.100339 |
| Popis: | Summary: Introduction: Escalation of chemical disinfection during the COVID-19 pandemic has raised occupational hazard concerns. Alternative and potentially safer methods such as ultraviolet-C (UVC) irradiation and ozone have been proposed, notwithstanding the lack of standardized criteria for their use in the healthcare environment. Aim: Compare the virucidal activity of 70% ethanol, sodium dichloroisocyanurate (NaDCC), chlorhexidine, ozonated water, UVC-222 nm, UVC-254 nm against three SARS-CoV-2 variants of concern cultured in vitro. Methods: Inactivation of three SARS-CoV-2 variants (alpha, beta, gamma) by the following chemical methods was tested: ethanol 70%, NaDCC (100 ppm, 500 ppm, 1000 ppm), chlorhexidine (2%, 1% and 0.5%), ozonated water 7 ppm. For irradiation, a je2Care 222nm UVC Lamp was compared to a Sylvania G15 UV254 nm lamp. Results: Viral inactivation by >3 log was achieved with ethanol, NaDCC and chlorhexidine. The minor virucidal effect of ozonated water was |
| Databáze: | Directory of Open Access Journals |
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