Autor: |
Ilona Argirion, Parag Mahale, Ruth M. Pfeiffer, Ping Liu, Adaora A. Adimora, Matthew J. Akiyama, Hector H. Bolivar, Audrey French, Michael Plankey, Jennifer C. Price, Aadia Rana, Anandi Sheth, Jill Koshiol, Eric C. Seaberg, Mark H. Kuniholm, Jeffrey Glenn, Thomas R. O’Brien |
Jazyk: |
angličtina |
Rok vydání: |
2023 |
Předmět: |
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Zdroj: |
Frontiers in Medicine, Vol 10 (2023) |
Druh dokumentu: |
article |
ISSN: |
2296-858X |
DOI: |
10.3389/fmed.2023.1070420 |
Popis: |
Hepatitis D virus (HDV) requires co-infection with hepatitis B virus (HBV). Human immunodeficiency virus (HIV) shares transmission routes with these viruses. Among 4,932 US women infected with or at-risk for HIV during 1994–2015, HBV surface antigen (HBsAg) positivity was more common in women with HIV (2.8% vs. 1.2%; p = 0.001); HDV was more common among participants enrolled during 2013–2015 (p = 0.0004) and those with resolved rather than active hepatitis C (1.9% vs. 0.5%; p = 0.02). Among HBsAg-positive women (n = 117), HDV antibody prevalence was 22% and did not vary by HIV status; HDV infection was associated with the presence of advanced fibrosis/cirrhosis at enrollment (adjusted odds ratio, 5.70; 95% confidence interval, 1.46–22.29). Our results demonstrate the importance of HDV testing in HBV-infected US women. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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