Usefulness of C-Reactive Protein as a Marker for Prediction of Future Coronary Events in the Asian Indian Population: Indian Atherosclerosis Research Study
| Autor: | Veena S. Rao, Natesha B. Kadarinarasimhiah, Shibu John, Sridhara Hebbagodi, Jayashree Shanker, Vijay V. Kakkar |
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| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: | |
| Zdroj: | International Journal of Vascular Medicine, Vol 2010 (2010) |
| Druh dokumentu: | article |
| ISSN: | 2090-2824 2090-2832 |
| DOI: | 10.1155/2010/389235 |
| Popis: | Inflammation plays a pivotal role in all stages of atherosclerosis. Numerous inflammatory, lipid, and cytokines markers have been associated with coronary artery disease (CAD) risk but data directly comparing their predictive value are limited. Studies were carried to elucidate the role of high-sensitivity C-reactive protein (hsCRP), other inflammatory as well as lipid markers and their associations. Among 1021 subjects, comprising 774 CAD affected members from Indian Atherosclerosis Research Study (IARS), plasma hsCRP levels showed strong correlation with inflammatory markers, namely, IL6 (r=.373; P=3.58 mg/L) were found to have a fourfold higher risk. In conclusion, hsCRP appears to be an independent predictor of recurrent CAD events in Asian Indian population. |
| Databáze: | Directory of Open Access Journals |
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