Sulforaphane alleviates oxidative stress induced by oxidized fish oil in Litopenaeus vannamei by involving antioxidant capacity, inflammation, autophagy, and apoptosis

Autor: Junliang Luo, Guojian Li, Yanghui Chen, Yunhao Yuan, Yongxiong Huang, Huiling Liu, Jichang Jian, Shuanghu Cai, Shiping Yang
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Aquaculture Reports, Vol 33, Iss , Pp 101851- (2023)
Druh dokumentu: article
ISSN: 2352-5134
DOI: 10.1016/j.aqrep.2023.101851
Popis: Sulforaphane (SFN) is an antioxidant. Unsaturated fatty acids are rich in fish oil, and they are indispensable fatty acids for aquatic animals to grow and reproduce. However, fish oil is easily oxidized, which could have adverse effects on aquatic animals. In this study, Litopenaeus vannamei was divided into four groups: fresh fish oil group (control group), oxidized fish oil group (OFO group), OFO plus low-concentration SFN group (OFO + SL group), and OFO plus high-concentration SFN group (OFO + SH group). A 28-day experiment was conducted, and the antioxidant capacity, inflammation, autophagy, and pathological characteristics were investigated to explore whether SFN could protect L. vannamei from oxidative stress induced by OFO. Results showed that OFO significantly increased the contents of MDA in hepatopancreas, muscle and serum, while high concentrations of SFN significantly decreased the MDA compared with the OFO group (P
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