Bovine Highly Pathogenic Avian Influenza Virus Stability and Inactivation in the Milk Byproduct Lactose

Autor: Taeyong Kwon, Jordan T. Gebhardt, Eu Lim Lyoo, Mohammed Nooruzzaman, Natasha N. Gaudreault, Igor Morozov, Diego G. Diel, Juergen A. Richt
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Viruses, Vol 16, Iss 9, p 1451 (2024)
Druh dokumentu: article
ISSN: 1999-4915
DOI: 10.3390/v16091451
Popis: The recent incursion of highly pathogenic influenza viruses into dairy cattle opens new insights for influenza virus ecology and its interspecies transmission and may have a significant impact on public health and agriculture. The aim of this study was to determine the stability of a bovine highly pathogenic avian influenza H5N1 virus isolate in the milk byproduct lactose and to evaluate two inactivation methods using industrial procedures. The bovine isolate of the highly pathogenic avian influenza H5N1 virus was stable for 14 days in a concentrated lactose solution under refrigerated conditions. Heat or citric acid treatments successfully inactivated the virus in lactose. This study highlights the persistence of HPAIV in lactose and its efficient inactivation under industrial standards.
Databáze: Directory of Open Access Journals
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