Primary intracranial melanoma

Autor: Po-Hsuan Lee, Liang-Chao Wang, E-Jian Lee
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Journal of Cancer Research and Practice, Vol 4, Iss 1, Pp 23-26 (2017)
Druh dokumentu: article
ISSN: 2311-3006
DOI: 10.1016/j.jcrpr.2016.09.001
Popis: Primary intracranial malignant melanomas are rarely reported tumors of the central nervous system that are highly malignant with a poor prognosis, accounting for 0.1% of intracranial neoplasms. Given the location of the tumor, preoperative diagnosis by imaging study is difficult. Typically, mainstream therapy involves total excision of the tumor followed by radiation therapy. We present a case of primary intracranial melanoma arising from convexity of the left frontal lobe in a 49-year-old male who presented with headache and progressive mentality change for one month. After total tumor excision and whole brain radiation therapy, the patient has experienced tumor-free survival extending through 47 months of follow-up. Herein we have reported the patient's MRI findings, pathological examination, treatment and outcome.
Databáze: Directory of Open Access Journals