Prognostic significance of the albumin-to-globulin ratio for upper tract urothelial carcinoma

Autor: Shota Omura, Satoru Taguchi, Shogo Miyagawa, Ryuki Matsumoto, Mio Samejima, Naoki Ninomiya, Kazuki Masuda, Yu Nakamura, Tsuyoshi Yamaguchi, Manami Kinjo, Mitsuhiro Tambo, Takatsugu Okegawa, Eiji Higashihara, Hiroshi Fukuhara
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: BMC Urology, Vol 20, Iss 1, Pp 1-7 (2020)
Druh dokumentu: article
ISSN: 1471-2490
DOI: 10.1186/s12894-020-00700-8
Popis: Abstract Background Although the albumin-to-globulin ratio (AGR) is a promising biomarker for various malignancies, few studies have investigated its prognostic significance for upper tract urothelial carcinoma (UTUC). Methods This retrospective study conformed to the REporting recommendations for tumour MARKer prognostic studies (REMARK) guideline. We reviewed 179 patients with UTUC who underwent radical nephroureterectomy at our institution between 2008 and 2018. Associations of preoperative clinicopathological factors, including the AGR, with cancer-specific survival (CSS) and overall survival (OS) were assessed. The Cox proportional hazards model was used for univariate and multivariable analyses. AGR was dichotomized as
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