Clustering and Erratic Movement Patterns of Syringe-Injected versus Mosquito-Inoculated Malaria Sporozoites Underlie Decreased Infectivity

Autor: C. M. de Korne, B. M. F. Winkel, M. N. van Oosterom, S. Chevalley-Maurel, H. M. Houwing, J. C. Sijtsma, S. Azargoshasb, E. Baalbergen, B. M. D. Franke-Fayard, F. W. B. van Leeuwen, M. Roestenberg
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: mSphere, Vol 6, Iss 2 (2021)
Druh dokumentu: article
ISSN: 2379-5042
DOI: 10.1128/mSphere.00218-21
Popis: Malaria still causes a major burden on global health and the economy. The efficacy of live, attenuated malaria sporozoites as vaccine candidates critically depends on their ability to migrate to and infect the host liver.
Databáze: Directory of Open Access Journals