Distribution and number of Cajal-like cells in testis tissue with azoospermia

Autor: Eray Hasirci, Tahsin Turunc, Nebil Bal, Mehmet Resit Goren, Huseyin Celik, Enis Kervancioglu, Ayhan Dirim, Mustafa Agah Tekindal, Hakan Ozkardes
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Kaohsiung Journal of Medical Sciences, Vol 33, Iss 4, Pp 181-186 (2017)
Druh dokumentu: article
ISSN: 1607-551X
DOI: 10.1016/j.kjms.2017.01.006
Popis: We investigated the number and distribution of Cajal-like cells in patients with azoospermia. A total of 99 patients with non-obstructive azoospermia were divided into subgroups [19 patientsin hypospermatogenesis group (S1), 40 patients in maturation arrest group (S2), 20 patients in a Sertoli cell-only syndrome (S3), and 20 patients in a testicular atrophy and fibrosis group (S4)], and 20 patients with obstructive azoospermia group (S0). Sections stained with a c-kit antibody were studied by light microscopy to determine the number and distribution of Cajal-like cells in peritubular and perivascular areas of testis. The number of Cajal-like cells were higher in all the non-obstructive groups than in the obstructive group (S0: 2.43 cells/mm2, S1: 3.14 cells/mm2, S2: 4.00 cells/mm2, S3: 4.57 cells/mm2, S4: 3.86 cells/mm2) but statistically significantly different (p
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