Quinazolinone and quinazoline derivatives: recent structures with potent antimicrobial and cytotoxic activities

Autor:	Elham Jafari, Marzieh Rahmani Khajouei, Farshid Hassanzadeh, Gholam Hossein Hakimelahi, Ghadam Ali Khodarahmi
Jazyk:	angličtina
Rok vydání:	2016
Předmět:	Quinazolinones Quinazoline Antimicrobial Cytotoxic Pharmacy and materia medica RS1-441
Zdroj:	Research in Pharmaceutical Sciences, Vol 11, Iss 1, Pp 1-14 (2016)
Druh dokumentu:	article
ISSN:	1735-5362 1735-9414
Popis:	The heterocyclic compounds have a great importance in medicinal chemistry. One of the most important heterocycles in medicinal chemistry are quinazolines possessing wide spectrum of biological properties like antibacterial, antifungal, anticonvulsant, anti-inflammatory, anti-HIV, anticancer and analgesic activities. This skeleton is an important pharmacophore considered as a privileged structure. This review highlights the recent advances in the synthesis of quinazolines and quinazolinone derivatives with potent antimicrobial and cytotoxic activities.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/f6e650701752494793c1a71640fd7b16 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF