Visceral basidiobolomycosis: An overlooked infection in immunocompetent children
| Autor: | Parkash Mandhan, Kamal Osman Hassan, Sandra Moustafa Samaan, Mansour J Ali |
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| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: | |
| Zdroj: | African Journal of Paediatric Surgery, Vol 12, Iss 3, Pp 193-196 (2015) |
| Druh dokumentu: | article |
| ISSN: | 0189-6725 0974-5998 |
| DOI: | 10.4103/0189-6725.170218 |
| Popis: | Visceral basidiobolomycosis is an unusual fungal infection of viscera caused by saprophyte Basidiobolus ranarum. It is very rare in healthy children and poses a diagnostic challenge due to the non-specific clinical presentation and the absence of predisposing factors. We report a case of gastrointestinal basidiobolomycosis in a 4-year-old healthy girl who presented with a short history of abdominal pain, bleeding per rectum, fever, and weight loss. The diagnosis was based on high eosinophilic count, classical histopathology findings of fungal hyphae (the Splendore-Hoeppli phenomenon), and positive fungal culture from a tissue biopsy. Fungal infection was successfully eradicated with a combined approach of surgical resection of the infected tissue and a well-monitored course of antifungal therapy. The atypical clinical presentation, diagnostic techniques, and the role of surgery in the management of a rare and lethal fungal disease in an immunocompetent child are discussed. |
| Databáze: | Directory of Open Access Journals |
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