Challenges of continuation of live liver donor programme during COVID-19 pandemic in Pakistan: outcomes and lessons learned

Autor: Azhar Hussain, Bilal Ahmed, Abdul Wahab Dogar, Shams Uddin, Syed Hasnain Abbas, Hala Izzo, Kaleem Ullah, Azam Shoaib, Siraj Ud Din, Muhammad Ameer Hamza, Munaza Zafar, Muhammad Affan Qaiser, Hamid Raza, Muhammad Asif Baig, Ali Husnain, Khalid Mumtaz
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: BMJ Open Gastroenterology, Vol 8, Iss 1 (2021)
Druh dokumentu: article
ISSN: 2054-4774
DOI: 10.1136/bmjgast-2021-000723
Popis: Background COVID-19 pandemic has globally affected healthcare including the transplantation programmes.Materials and methods We retrospectively studied the impact of COVID-19 on live liver donor (LLD) programme at liver transplant centre in Gambat, Pakistan. Standard operative procedures (SOPs) including COVID-19 nasopharyngeal swab PCR, CT scans, personal protective equipment use, 6-feet distancing were developed for LLD and transplant team to mitigate COVID-19 exposure. We compared the complications, healthcare utilisation (hospital stay, readmission) and mortality between two LLD cohorts—before and during COVID-19 pandemic from March 2019 to December 2020.Results During study period 300 LLD surgeries were performed. There was an increase in rate of LLDs from 132 (44%) in pre-COVID to 168 (56%) during COVID-19 era. Average numbers of transplants per month performed during pre-COVID and during COVID-19 era were 10.1 and 14, respectively. No donor has developed COVID-19 infection during hospitalisation. Rate of all LLD complications (32 (21.47%) and 49 (29.16%), p=0.43), uneventful discharges (120/168 (71.4%) and 88/132 (66.6%), p
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