Myocardial Performance Index to assess cardiac function in autoimmune connective tissue disease: a systematic review and meta-analysis

Autor: Rudy Hidayat, Sally Aman Nasution, Faisal Parlindungan, Naomi Niari Dalimunthe, Steven Alvianto, Nicolas Daniel Widjanarko, Ummi Kultsum, Cristopher Efendi, Yovita Gotama
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Lupus Science and Medicine, Vol 11, Iss 2 (2024)
Druh dokumentu: article
ISSN: 2053-8790
40246930
DOI: 10.1136/lupus-2024-001272
Popis: Objectives This study aimed to evaluate cardiac function using Myocardial Performance Index (MPI) in autoimmune connective tissue disease (ACTD) patients without cardiovascular abnormalities.Methods A systematic search of databases including Medline, Google Scholar, ProQuest, Scopus and Cochrane Library was conducted to identify relevant studies on ACTD and MPI from 1995 to 2023. ACTD included in the search were rheumatoid arthritis (RA), systemic sclerosis (SSc), systemic lupus erythematosus (SLE), Sjögren syndrome (SjD), polymyositis and dermatomyositis. Quality assessment was performed using the Newcastle-Ottawa Scale, followed by meta-analysis computation of mean differences (MDs) of MPI using Review Manager V.5.4.Results A total of 22 studies for qualitative and 19 for quantitative synthesis were included. We found six studies on RA, eight studies on SSc, five studies on SLE, two studies on SjD and one on mixed connective tissue disorder. Conventional echocardiography and tissue Doppler imaging (TDI) were used to assess the MPI. Both conventional MPI and tissue Doppler MPI values were elevated compared with healthy control (MD=0.11, 95% CI 0.08 to 0.14, p value
Databáze: Directory of Open Access Journals