Autor: |
Maria D. Purice, Sean D. Speese, Mary A. Logan |
Jazyk: |
angličtina |
Rok vydání: |
2016 |
Předmět: |
|
Zdroj: |
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016) |
Druh dokumentu: |
article |
ISSN: |
2041-1723 |
DOI: |
10.1038/ncomms12871 |
Popis: |
Glial engulfment declines with age, but the mechanism is unclear. Here authors show that in the Drosophilaolfactory system, glial phagocytosis of injury-induced degenerating axons decreases with age due to reduced PI3K/Draper activity, and restoring Draper in aged glia rescues such defects. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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