Chronic Wasting Disease Prion Strain Emergence and Host Range Expansion
Autor: | Allen Herbst, Camilo Duque Velásquez, Elizabeth Triscott, Judd M. Aiken, Debbie McKenzie |
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Jazyk: | angličtina |
Rok vydání: | 2017 |
Předmět: | |
Zdroj: | Emerging Infectious Diseases, Vol 23, Iss 9, Pp 1598-1600 (2017) |
Druh dokumentu: | article |
ISSN: | 1080-6040 1080-6059 |
DOI: | 10.3201/eid2309.161474 |
Popis: | Human and mouse prion proteins share a structural motif that regulates resistance to common chronic wasting disease (CWD) prion strains. Successful transmission of an emergent strain of CWD prion, H95+, into mice resulted in infection. Thus, emergent CWD prion strains may have higher zoonotic potential than common strains. |
Databáze: | Directory of Open Access Journals |
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