Chronic Wasting Disease Prion Strain Emergence and Host Range Expansion

Autor: Allen Herbst, Camilo Duque Velásquez, Elizabeth Triscott, Judd M. Aiken, Debbie McKenzie
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Emerging Infectious Diseases, Vol 23, Iss 9, Pp 1598-1600 (2017)
Druh dokumentu: article
ISSN: 1080-6040
1080-6059
DOI: 10.3201/eid2309.161474
Popis: Human and mouse prion proteins share a structural motif that regulates resistance to common chronic wasting disease (CWD) prion strains. Successful transmission of an emergent strain of CWD prion, H95+, into mice resulted in infection. Thus, emergent CWD prion strains may have higher zoonotic potential than common strains.
Databáze: Directory of Open Access Journals