Building the Frequency Profile of the Core Promoter Element Patterns in the Three ChromHMM Promoter States at 200bp Intervals: A Statistical Perspective
| Autor: | Heather Lent, Kyung-Eun Lee, Hyun-Seok Park |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: | |
| Zdroj: | Genomics & Informatics, Vol 13, Iss 4, Pp 152-155 (2015) |
| Druh dokumentu: | article |
| ISSN: | 1598-866X 2234-0742 |
| DOI: | 10.5808/GI.2015.13.4.152 |
| Popis: | Recently, the Encyclopedia of DNA Elements (ENCODE) Analysis Working Group converted data from ChIP-seq analyses from the Broad Histone track into 15 corresponding chromatic maps that label sequences with different kinds of histone modifications in promoter regions. Here, we publish a frequency profile of the three ChromHMM promoter states, at 200-bp intervals, with particular reference to the existence of sequence patterns of promoter elements, GC-richness, and transcription starting sites. Through detailed and diligent analysis of promoter regions, researchers will be able to uncover new and significant information about transcription initiation and gene function. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|