Immediate effects of cigar smoking on respiratory mechanics and exhaled biomarkers; differences between young smokers with mild asthma and otherwise healthy young smokers

Autor: Andreas S. Lappas, Efstathia M. Konstantinidi, Anna S. Tzortzi, Chara K. Tzavara, Panagiotis K. Behrakis
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Tobacco Induced Diseases, Vol 14, Iss August (2016)
Druh dokumentu: article
ISSN: 1617-9625
DOI: 10.1186/s12971-016-0095-6
Popis: Introduction We aimed to investigate the immediate respiratory effects of cigar smoking(CS), among young smokers with and without mild asthma. Material and Methods Forty-seven young smokers (18–31years old, 29 males, average pack-years = 3.6 ± 2.8) were enrolled. Twenty-two were mild asthmatics(MA-subgroup) and the remaining 25 were otherwise healthy smokers(HS-subgroup). Exhaled carbon monoxide(eCO), multi-frequency respiratory system impedance(Z), resistance(R), reactance(X), frequency-dependence of resistance(fdr = R5Hz - R20Hz), resonant frequency(fres), reactance area(AX) and exhaled nitric oxide(FENO) were measured at the aforementioned sequence, before and immediately after 30 min of CS, or equal session in the smoking area while using a sham cigar(control group). Chi-square, student’s t-tests, mixed linear models and Pearson correlation tests were used for the statistical analysis; level of significance was defined as p
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