| Autor: |
Noelle A. Benzekri, Jacques F. Sambou, Sanou Ndong, Ibrahima Tito Tamba, Dominique Faye, Mouhamadou Baïla Diallo, Jean Phillippe Diatta, Khadim Faye, Ibrahima Sall, Fatima Sall, Noël Magloire Manga, Jean Jacques Malomar, Cheikh T. Ndour, Stephen E. Hawes, Moussa Seydi, Geoffrey S. Gottlieb |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
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| Zdroj: |
BMC Infectious Diseases, Vol 19, Iss 1, Pp 1-8 (2019) |
| Druh dokumentu: |
article |
| ISSN: |
1471-2334 |
| DOI: |
10.1186/s12879-019-3826-5 |
| Popis: |
Abstract Background The WHO guidelines for the management of advanced HIV disease recommend a package of care consisting of rapid initiation of antiretroviral therapy (ART), enhanced screening and diagnosis of tuberculosis (TB) and cryptococcal meningitis, co-trimoxazole prophylaxis, isoniazid preventive therapy (IPT), fluconazole pre-emptive therapy, and adherence support. The goals of this study were to determine the prevalence of advanced HIV disease among individuals initiating ART in Senegal, to identify predictors of advanced disease, and to evaluate adherence to the WHO guidelines. Methods This study was conducted among HIV-positive individuals initiating ART in Dakar and Ziguinchor, Senegal. Clinical evaluations, laboratory analyses, questionnaires and chart review were conducted. Logistic regression was used to identify predictors of advanced disease. Results A total of 198 subjects were enrolled; 70% were female. The majority of subjects (71%) had advanced HIV disease, defined by the WHO as a CD4 count |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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