Abstract 1122‐000171: Unusual Multicompartmental Intracranial Hemorrhage After Tenecteplase Administration

Autor: Abdallah Amireh, Muhammad Nagy, Hassan Ali, Siddhart Mehta, Haralabos Zacharatos, Farah Fourcand, Jawad Kirmani
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Stroke: Vascular and Interventional Neurology, Vol 1, Iss S1 (2021)
Druh dokumentu: article
ISSN: 2694-5746
DOI: 10.1161/SVIN.01.suppl_1.000171
Popis: Introduction: The 2019 AHA/ASA updated Guidelines for the Early Management of Patients with Acute Ischemic Stroke mention tenecteplase (TNK) as a reasonable therapy in patients without contraindications for IV fibrinolysis who are also eligible to undergo mechanical thrombectomy. We describe a case of acute left MCA ischemic stroke treated with IV TNK (IV bolus of 0.25 mg/kg) followed by mechanical thrombectomy with subsequent multicompartmental intracranial hemorrhages unrelated to area of infraction. Methods: A retrospective review at a single center university hospital was performed for all intravenous TNK administrations outside of a clinical trial setting from October 2020 to July 2021. Results: A 61‐year‐old male with history of HTN and cardiomyopathy (EF
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