Long-term outcomes of 307 patients after complete thymoma resection

Autor: Zu-Yang Yuan, Shu-Geng Gao, Ju-Wei Mu, Qi Xue, You-Sheng Mao, Da-Li Wang, Jun Zhao, Yu-Shun Gao, Jin-Feng Huang, Jie He
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Chinese Journal of Cancer, Vol 36, Iss 1, Pp 1-9 (2017)
Druh dokumentu: article
ISSN: 1944-446X
DOI: 10.1186/s40880-017-0213-8
Popis: Abstract Background Thymoma is an uncommon tumor without a widely accepted standard care to date. We aimed to investigate the clinicopathologic variables of patients with thymoma and identify possible predictors of survival and recurrence after initial resection. Methods We retrospectively selected 307 patients with thymoma who underwent complete resection at the Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College (Beijing, China) between January 2003 and December 2014. The associations of patients’ clinical characteristics with prognosis were estimated using Cox regression and Kaplan–Meier survival analyses. Results During follow-up (median, 86 months; range, 24–160 months), the 5- and 10-year disease-free survival (DFS) rates were 84.0% and 73.0%, respectively, and the 5- and 10-year overall survival (OS) rates were 91.0% and 74.0%, respectively. Masaoka stage (P
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