The evaluation of PIK3CA gene variation and serum PI3K level in breast cancer risk and prognosis in Turkish population
| Autor: | Ulu Elif, Yaylım İlhan, Arıkan Soykan, Cacına Canan |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
apoptosis
breast cancer phosphatidylinositol-4 5-bisphosphate 3-kinase catalytic subunit alpha (pik3ca) serum level single nucleotide polymorphism (snp) apoptoz meme kanseri fosfatidilinozitol-4 5-bifosfat 3-kinaz katalitik alt birim alfa (pik3ca) serum düzeyi tek nükleotid polimorfizmi (snp) Biochemistry QD415-436 |
| Zdroj: | Türk Biyokimya Dergisi, Vol 47, Iss 3, Pp 317-324 (2021) |
| Druh dokumentu: | article |
| ISSN: | 1303-829X |
| DOI: | 10.1515/tjb-2021-0072 |
| Popis: | The PI3K (Phosphatidylinositol 3-kinase) is the member of lipid kinase family that plays important roles in tumorigenesis, cancer development and cell proliferation. In our study, we aimed to investigate the relationships between breast cancer risk and prognosis with PIK3CA rs6443624 (C>A) intron region gene polymorphism and serum PI3K levels. |
| Databáze: | Directory of Open Access Journals |
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