| Autor: |
Elżbieta Cecerska-Heryć, Dominika Nieszpór, Natalia Serwin, Ewa Pius Sadowska, Marta Gliźniewicz, Bartłomiej Grygorcewicz, Karol Serwin, Anna Michalczyk, Marta Budkowska, Małgorzata Goszka, Aleksandra Polikowska, Radosław Birger, Bogusław Machaliński, Barbara Dołęgowska |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
Mediators of Inflammation, Vol 2024 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
1466-1861 |
| DOI: |
10.1155/2024/3838845 |
| Popis: |
Platelets are the first to reach the site of tissue damage and secrete substances like platelet growth factors (GFs), which perform many different functions in the human body. Many studies suggest that GFs such as transforming GF (TGF), platelet-derived GF (PDGF), or insulin-like GF-1 (IGF-1) may be markers of survival, disease severity, and post-coronavirus disease (COVID) complications. The study aimed to analyze the concentration of TGF-β, IGF-1, and PDGF-BB in COVID-19 patients compared to the control group (GK). The study group consisted of 50 patients (23 men and 27 women) at the time of COVID-19 detection, 7 days after detection, then 14 and 28 days after detecting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The GK comprised 48 healthy volunteers (25 women and 23 men). IGF-1, TGF-β, and PDGF-BB concentrations in blood serum by enzyme-linked immunosorbent assay (ELISA) methods. There was a statistically significant relationship between the concentration of IGF-1, TGF-β 1, and PDGF-BB in the study group (I–IV blood draw) and the GK (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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