| Autor: |
Luke R. Perreault, Mark C. Daley, Matthew C. Watson, Sagar Rastogi, Ajith Jaiganesh, Elizabeth C. Porter, Breanna M. Duffy, Lauren D. Black |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
|
| Zdroj: |
Frontiers in Cell and Developmental Biology, Vol 12 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2296-634X |
| DOI: |
10.3389/fcell.2024.1279932 |
| Popis: |
Heart failure afflicts an estimated 6.5 million people in the United States, driven largely by incidents of coronary heart disease (CHD). CHD leads to heart failure due to the inability of adult myocardial tissue to regenerate after myocardial infarction (MI). Instead, immune cells and resident cardiac fibroblasts (CFs), the cells responsible for the maintenance of the cardiac extracellular matrix (cECM), drive an inflammatory wound healing response, which leads to fibrotic scar tissue. However, fibrosis is reduced in fetal and early ( |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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