Primary Ovarian Choriocarcinoma: Rare Entity

Autor: Mequanent Tariku Adow, Shimelis Fantu Gebresilasie, Natnael Alemayehu Abebe
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Case Reports in Obstetrics and Gynecology, Vol 2021 (2021)
Druh dokumentu: article
ISSN: 2090-6684
2090-6692
DOI: 10.1155/2021/4545375
Popis: Background. Primary pure ovarian choriocarcinoma is a rare aggressive tumor which can be nongestational arising from germ cells or gestational origin. Preoperative diagnosis of extrauterine choriocarcinoma is challenging due to nonspecific clinical presentation. Case Presentation. This article reports primary ovarian choriocarcinoma, likely gestational in a 25-year-old para 2 woman presenting with lower abdominal pain and swelling of two-week duration. Diagnosis was suspected by serum beta-human chorionic gonadotropin and confirmed histologically after surgery. Postoperatively, she was managed with multiple courses of chemotherapy using a bleomycin, etoposide, and cisplatin regimen, and the treatment was effective. Conclusion. In patients with adnexal mass presenting with nonspecific symptoms especially with high Doppler blood flow of the mass on ultrasound evaluation, serum beta-human chorionic gonadotropin determination is recommended before laparotomy. In setups where the genomic test is not available, histological and clinical effort to differentiate gestational versus nongestational choriocarcinoma is useful for specific management decision.
Databáze: Directory of Open Access Journals
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