Ophthalmic findings in sheep treated with closantel in Curitiba, Brazil
| Autor: | Marianna Bacellar-Galdino, Fabiano Montiani-Ferreira, Andre Tavares Somma, Ricardo Guilherme D'Otaviano de Castro Vilani, Ivan Roque de Barros Filho |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | Veterinary World, Vol 13, Iss 5, Pp 860-864 (2020) |
| Druh dokumentu: | article |
| ISSN: | 0972-8988 2231-0916 |
| DOI: | 10.14202/vetworld.2020.860-864 |
| Popis: | Background and Aim: Closantel is a widely used anti-parasitic drug that is known to cause ophthalmic problems that lead to blindness. The aim of this study was to investigate the possible electroretinographic changes in sheep that received closantel. Materials and Methods: Twenty-four 30-day-old Suffolk sheep were split into control group (12 animals) and closantel group (12 animals). The latter group received 15 mg/kg of closantel subcutaneously immediately after the first electroretinography (ERG). The ISCEV protocol was used to perform the ERGs pre-dose (0), 7, and 30 days after treatment. Statistical analyses to compare ERG responses using t-test and analysis of variance were performed (p |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
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