Bilateral Charcot Neuroarthropathy in Pregnancy: A Case Report and Review of the Influence of Pregnancy Hormones on Ligament Laxity

Autor: Rebecca Rogers, MBBS, MRCP, Ketan K. Dhatariya, MBBS, MSc, MD, MS, PhD
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: AACE Clinical Case Reports, Vol 7, Iss 1, Pp 57-60 (2021)
Druh dokumentu: article
ISSN: 2376-0605
DOI: 10.1016/j.aace.2020.11.015
Popis: Objective: To describe the case of a woman with long-standing poorly controlled type 1 diabetes mellitus who developed bilateral Charcot foot while pregnant. To the best of our knowledge, this is the first reported case of this condition in pregnancy. Methods: We performed a retrospective review of physical paper medical records; electronically held laboratory results, including glycated hemoglobin; and imaging reports, including plain radiographs and magnetic resonance imaging. Results: The Charcot feet were treated by standard offloading in total-contact casts or below-knee removable walking boots. As 1 side resolved, the patient was stepped down into normal footwear on one side and a below-knee walking boot on the other. A review of the literature suggests that the increase in ligamentous laxity associated with a rise in circulating hormones, such as relaxin, increases the risk of developing Charcot neuroarthropathy. Conclusion: Bilateral concurrent Charcot neuroarthropathic foot is uncommon, and to our knowledge, this is the first reported case in pregnancy. We present a possible explanation for why there is an increased risk for the development of Charcot neuroarthropathy in pregnancy.
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