A Case Report of Spindle Cell (Sarcomatoid) Carcinoma of the Larynx

Autor: Harry Boamah, Billy Ballard
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: Case Reports in Medicine, Vol 2012 (2012)
Druh dokumentu: article
ISSN: 1687-9627
1687-9635
87461595
DOI: 10.1155/2012/370204
Popis: Spindle cell carcinoma (SpCC) or sarcomatoid carcinoma is a highly malignant variant of squamous cell carcinoma which comprises 2% to 3% of all laryngeal cancers. It is considered to be a biphasic tumor that is composed of a squamous cell carcinoma (in situ or invasive) and spindle cell carcinoma with sarcomatous appearance. Most spindle cell tumors are polypoid and pedunculated; they are often detected at an early stage, removed by polypectomy during diagnosis, and tend to have a very good prognosis. We present a case of spindle cell carcinoma in a 67-year-old Caucasian male who presented with progressive hoarseness of his voice, dysphagia, odynophagia and a 20-pound weight loss. The patient underwent direct laryngoscopy with excision of the malignant mass and received radiation therapy. His symptoms gradually improved, and he regained good control of his voice.
Databáze: Directory of Open Access Journals