Vitamin D deficiency in patients with cystic fibrosis: a systematic review and meta-analysis

Autor: Nazanin Farahbakhsh, Somaye Fatahi, Armin Shirvani, Monireh Sadat Motaharifard, Masoumeh Mohkam, Seyed Ahmad Tabatabaii, Ghamartaj khanbabaee, Shirin Yaghoobpoor, Seyedeh Zahra Davoodi, Amir hossein Hosseini
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Journal of Health, Population and Nutrition, Vol 43, Iss 1, Pp 1-15 (2024)
Druh dokumentu: article
ISSN: 2072-1315
DOI: 10.1186/s41043-024-00499-2
Popis: Abstract Aim Vitamin D is a prominent modulator of immunity and respiratory function. It plays a vital role in respiratory diseases such as cystic fibrosis (CF). S. However, there is a dearth of information on patients with CF. The purpose of the meta-analysis is to highlight the importance of following the existing guidelines regarding maintenance of Vitamin D serum levels in patients with CF. Methods The systematic search was conducted without utilizing any time or language limitations in original database from the beginning until March 2022. The meta-analysis was performed using a random-effects model. Heterogeneity was determined by I 2 statistics and Cochrane Q test. Results Pooled analysis using the random-effects model of the 8 case–control studies with 13 effect sizes revealed that the serum 25-OH-vitamin D in participants with cystic fibrosis was significantly lower than controls in pediatrics and adolescences (WMD: − 3.41 ng/ml, 95% CI − 5.02, − 1.80, p =
Databáze: Directory of Open Access Journals
Nepřihlášeným uživatelům se plný text nezobrazuje